Acute Monarticular Arthritis After Vaccination

Case Studies1 February 1965Acute Monarticular Arthritis After VaccinationReport of a Case with Isolation of Vaccinia Virus from Synovial FluidHOWARD M. SILBY, M.D., ROGER FARBER, M.D., CORNELIUS J. O'CONNELL, M.D., JULIAN ASCHER, M.D., EDWARD J. MARINE, M.D.HOWARD M. SILBY, M.D., ROGER FARBER, M.D., CORNELIUS J. O'CONNELL, M.D., JULIAN ASCHER, M.D., EDWARD J. MARINE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-2-347 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptArthritis has been described as an occasional complication of several viral diseases. However, to the authors' knowledge, the isolation of a specific virus from human synovial fluid in such cases has not been reported previously. The present report documents a case of acute monarticular arthritis after smallpox vaccination in which vaccinia virus was recovered from the synovial fluid.CASE REPORTE. J. (BGH 293446), a 65-year-old Negro female, was admitted to the Buffalo General Hospital on June 25, 1963, because of fever and a painful swelling of the right knee. Twelve days previously, at her request, she had been vaccinated...References1. KEMPE CH: Diagnostic Procedures for Viral and Rickettsial Diseases: Variola and Vaccinia, 2nd ed., American Public Health Association, New York, 1956. Google Scholar2. CUTCHINSWAVENJONES EJWP: The antibody response to smallpox vaccination as measured by a tissue culture plaque method. J. Immun. 85: 275, 1960. MedlineGoogle Scholar3. FAGRAEUSESPMARK A#: Use of a 'mixed haemadsorption' method in virus-infected tissue cultures. Nature (London) 190: 370, 1961. CrossrefMedlineGoogle Scholar4. BARRONMILGROMKARZONWITEBSKY ALEDE: Demonstration of human measles antibody by mixed agglutination. J. Immun. 90: 908, 1963. MedlineGoogle Scholar5. BRINKMAN E: Frühzeitige epiphysenverknöcherung und osteomyelitis variolosa. Z. Orthop. Chir. 57: 208, 1932. 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Marine, USAF(MC), Department of Medicine, Davis-Monthan Air Force Base, Tucson, Ariz. 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SMITH, M.D., JAY P. SANFORD, M.D., F.A.C.P.Rubella Synovitis in a One-Year-Old PatientCardiac Complications of Progressive Generalized VacciniaBone and joint involvement in virus disease 1 February 1965Volume 62, Issue 2Page: 347-350KeywordsArthritisHospital medicineImmunologyInflammationKneesPathogenesisSmallpoxSynovial fluidViral diseasesViremia Issue Published: 1 February 1965 PDF downloadLoading ...