In Brief Among gonococcal isolates examined at the Hawaii State Laboratory Division from 2003 to 2011, the prevalence of elevated cefixime minimum inhibitory concentrations (MICs; ≥0.064 μg/mL) and elevated cefpodoxime MICs (≥0.19 μg/mL) increased over time. In contrast, few isolates exhibited elevated ceftriaxone MICs (≥0.094 μg/mL), and the prevalence of elevated ceftriaxone MICs did not change. An analysis of gonococcal isolates in Hawaii found that the prevalence of elevated cefixime minimum inhibitory concentrations increased in 2003 to 2011, but prevalence of elevated ceftriaxone minimum inhibitory concentrations did not.
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Kidd et al. (2013) studied this question.
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