ratio [HR]1.19, p<0.01 ), but this association was not statistically significant in multivariable analysis. At 5-years post-surgery, overall survival in the PN group was 75% vs. 68% in the RN group. (p<0.001) (Figure Compared with PN, RN was associated with an increased risk of death from any cause (HR 1.29, p<0.001 ), controlling for age, sex, race, marital status, general comorbidity and pre-existing CV disease. CONCLUSIONS: In this population-based cohort, RN was associated with a significantly increased risk of overall mortality and a trend towards increased CV events. Because patients with small, curable RTs undergoing RN are at increased risk for significant long-term morbidity and mortality, RN should be avoided in these patients when possible.
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Lane et al. (2007) studied this question.