Fiber-like supermolecular structures having hierarchical order are formed from the coassembly of stereoregular poly(ethylene glycol)-block-polylactide (PEG-b-PLA) block copolymers with paclitaxel, a well-known anticancer drug (see image). Importantly, these paclitaxel- loaded block copolymer complexes possess a PEG shell, show stable sustained release of the drug under simulated physiological conditions, and have great potential in clinical applications for localized drug delivery.
No takes yet. Share an insight, caveat, or question.
Tan et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: