A 16-week interval increases B cell response and maturity compared to a 3-week delay A 16-week interval has limited impact on the magnitude of CD4 and CD8 T cell responses A long interval is associated with an early increase of specific SARS-CoV-2 cTfh T cell phenotypes in 16-week versus 3-week regimens converge at late time points
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Nicolas et al. (2022) studied this question.
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