The NMR study on the interactions of 2′-dG with Mg2+, Zn2+ and Hg2+ ions in D2O solution has shown that binding of softer metal ions to N7 shifts N <!—graphic—> S pseudorotational equilibrium slightly towards N-type sugar conformations. There are no detectable changes for the conformational equilibria across C4′-C5′ bond, whereas the population of the syn conformers is slightly increased.
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Polak et al. (1998) studied this question.
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