Rhinosinusitis (RS) may be sub-classified into several groups based on duration of symptoms, etiology, associated clinical history, and findings during endoscopic nasal examination. While one may dissect RS into several subgroups, the four major clinical categories are Recurrent Acute Rhinosinusitis (RARS), Chronic Rhinosinusitis without Nasal Polyps (CRSsNP), Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), and Hyperplastic Rhinosinusitis (HRS). The American academy of Otolaryngology defines RARS as 4 or more acute infections per year of acute bacterial rhinosinusitis [1] lasting < 12 weeks. CRS is an inflammatory condition requiring the presence of 2 or more symptoms; one of which should be nasal discharge or nasal obstruction/blockage/congestion, +/-facial pain, +/-reduced or absent sense of smell, for 12 weeks or more. In addition, endoscopic findings or CT images showing pathological changes in the middle meat us should be present. CRS may exist with Nasal Polyps (CRSwNP) or without Nasal Polyps (CRSsNP). Extensive nasal polyposis may also be driven by allergic fungal sinusitis or by aspirin sensitivity in a subset of patients with asthma and nasal polyposis (Samter's triad) The latter two groups have been collectively referred to as Hyperplastic Rhinosinusitis (HRS) by Kennedy and Borish [3], and will be referred to as such for the purposes of this study.
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Peter J. Catalano (2015) studied this question.
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