Subjective and Objective Outcome Evaluation of FESS with and without Mitomycin C: A Randomized Control Trial

Materials and Methods: Total 150 patients between” May 2011 to July 2014 with clinical and CT features of chronic rhino sinusitis, not responding to maximal medical treatment, were subjected to endoscopic sinus surgery (ESS/FESS).75 patients were included in Group A (Interventional-MMC) and 75 patients in group B (Control-Saline). There were 30 unilateral and 45 bilateral, thus 120 operative sides in each group. Follow up visits were done at weekly for first two weeks and then at 1st, 2nd and 3rd month and subjective parameters evaluated included total score and individual symptom score of 4 symptoms-Facial pain/pressure, Nasal block, Discharge and Hyposmia, SNOT-20 score and its 4 domainsRhinologic domain, Ear & facial domain, Sleep and Psychologic domains.