Why the study?
Do calcium-channel-blocking drugs increase renal sodium excretion in animals and humans?
Do calcium-channel-blocking drugs increase renal sodium excretion in animals and humans?
Calcium-channel blockers exert clinically important natriuretic effects through both hemodynamic and direct tubular mechanisms.
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May support natriuretic strategies in hypertension; leaves open prospective outcome trials before practice change.
Friedrich C. Luft (2008) studied this question.
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