Asymmetric Catalytic Routes to Dialkyl Peroxides and Oxaziridines

Enantioenriched dialkyl peroxides and oxaziridines are two classes of compounds showing important biological activities, being useful synthetic intermediates and reagents for asymmetric oxidations and cycloaddition reactions. Chiral substrate-controlled diastereoselective preparations of these compounds have been developed almost exclusively in the last decades. The aim of this perspective article is to provide the reader with recent efforts devoted to addressing the challenging task of their synthesis via either enantioselective organo- and transition metal-catalyzed oxidations or via alternative nonoxidative approaches.