The significance of the interaction between aluminum and citrate in biological media is exemplified by the synthesis, isolation, structural characterization, and solution behavior of the first mononuclear aluminum citrate complex. The chemical and structural features of the low molecular weight aluminum citrate species characterized help gain insight into citrate's ability, as a natural ligand, to enhance aluminum's absorption and thus affect its accumulation and biotoxicity at biological sites.
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Matzapetákis et al. (1999) studied this question.
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