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A new crystalline substance has been isolated from hog adrenals in a yield of about 30 mg per 1000 kg glands. It appears to act under certain biological conditions as a sodium excreting factor. This compound is shown to be 3β,16α‐dihydroxy‐allopregnan‐20‐one; several syntheses of it as well as a number of derivatives are described.
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Neher et al. (1958) studied this question.
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