January 1, 1989Circulation
Rapid reduction of plasma atrial natriuretic peptide levels during percutaneous transvenous mitral commissurotomy in patients with mitral stenosis.
Why the study?
Does percutaneous transvenous mitral commissurotomy reduce plasma human atrial natriuretic peptide levels in patients with mitral stenosis?
Population
13 patients with mitral stenosis undergoing percutaneous transvenous mitral commissurotomy (PTMC)
Comparison
Percutaneous transvenous mitral commissurotomy vs Pre-procedural baseline (before PTMC)
Design
Cohort
Follow-up
Immediate post-procedure
Authors
Discussion
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Member takes
Implication
Supports left atrial pressure as regulator of hANP in mitral stenosis; leaves open outcome implications after PTMC.
Structured PICO
Does percutaneous transvenous mitral commissurotomy reduce plasma human atrial natriuretic peptide levels in patients with mitral stenosis?
P
Population
13 patients with mitral stenosis undergoing percutaneous transvenous mitral commissurotomy (PTMC)
I
Intervention
Percutaneous transvenous mitral commissurotomy (PTMC)
C
Comparator
Pre-procedural baseline (before PTMC)
O
Outcome
Changes in plasma human atrial natriuretic peptide (hANP) levels and left atrial pressuresurrogate
The rapid reduction of left atrial pressure during PTMC is directly correlated with a significant decrease in plasma hANP levels, highlighting the role of left atrial pressure in hANP secretion.
Cite This Study
Ishikura et al. (1989) studied this question.