Letters and Corrections1 April 1985Diltiazem and Generalized LymphadenopathyBARBARA SCOLNICK, M.D., DON BRINBERG, M.D.BARBARA SCOLNICK, M.D., DON BRINBERG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-4-558_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We report the case of a patient being treated with diltiazem who developed a severe hypersensitivity reaction that presented clinically as a generalized lymphadenopathy and skin rash; the reaction resolved after withdrawal of the drug.A 50-year-old patient with known coronary artery disease, hypertension, hyperlipidemia, and chronic vertigo was maintained on isosorbide dinitrate, 20 mg four times a day; nadolol, 40 mg once a day; hydrochlorthiazide, 50 mg once a day; nitroglycerin, 10 mg once a day; meclizine, 25 mg three times a day; and probucol, 500 mg twice a day. On 19 May 1984 he was...References1. MCGRAW B. Diltiazem hydrochloride. Drug Intell Clin Pharm. 1982;16:366-8. CrossrefMedlineGoogle Scholar2. MCGRAWWALKERHEMBERGERGITOMERNAKAMA BSJSM. Clinical experience with diltiazem in Japan. Pharmacotherapy. 1982;2:156-61. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brockton/West Roxbury Veterans Medical Center West Roxbury, MA 02132 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe spectrum of nephrocutaneous diseases and associationsCalcium channel blockersDiltiazem☆Drug ReactionsAdverse immunological effects of drugs other than anticance drugs and drugs used in immunologyDrugs Used to Treat Hypertension, Heart Failure, and Angina PectorisCalcium channel blockersThe spectrum of cutaneous reactions associated with diltiazem: Three cases and a review of the literatureDrug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS)SKIN REACTIONS TO DILTIAZEMProbleme bei der Behandlung mit KalziumantagonistenReports of Erythematous Macular Skin Eruptions Associated with Diltiazem TherapySide Effects — Overdosage — Contraindications — Drug InteractionsAngioedema from calcium channel blockersNebenwirkungen — Überdosierung (Vergiftung) — Kontraindikationen — ArzneimittelinteraktionenKalziumantagonistenAntianginal and β-adrenoceptor antagonistsAntianginal and β-adrenoceptor blocking drugs 1 April 1985Volume 102, Issue 4Page: 558-558KeywordsDrugsHyperlipidemiaHypersensitivityHypertensionRashesStable coronary artery diseaseVertigo Issue Published: 1 April 1985 PDF downloadLoading ...
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Barbara Scolnick (1985) studied this question.
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