Cutaneous spindle cell neoplasms may cause considerable problems in the diagnosis and proper treatment of affected patients. After exclusion of nonmesenchymal spindle cell lesions, including /spindle cell (sarcomatoid) carcinoma as well as spindle cell and desmoplastic melanoma, the line of differentiation and the dignity must be established. Immunohistochemical stainings are very important in this process, and a number of examples of cutaneous spindle cell neoplasms are described.
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Thomas Mentzel (2026) studied this question.
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