A novel apparatus for characterization and control of isolated muscle tissue provides generalized mechanical boundary conditions and real-time feedback control for fundamental investigations of muscle mechanics.
Caution against clinical translation from this animal pilot; extends isolated muscle mechanics research with novel boundary conditions.
An apparatus for characterization and control of muscle tissue is presented. The apparatus is capable of providing generalized mechanical boundary conditions to muscle tissue, as well as implementing real-time feedback control via electrical stimulation. The system is intended to serve as an experimental platform for implementing a wide variety of muscle control and identification studies that will serve as fundamental investigations of muscle mechanics, energetics, functional electrical stimulation, and fatigue. In one illustration of the capabilities of the apparatus, pilot experimental results of muscle workloops against a finite-admittance passive load are presented, illustrating how richer boundary conditions may reveal interesting muscle behavior.
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Farahat et al. (2005) studied this question.
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