Why the study?
Does the presence of diffuse white matter changes on brain MRI correlate with fine motor and perceptuo-motor deficits in children with congenital muscular dystrophy?
Does the presence of diffuse white matter changes on brain MRI correlate with fine motor and perceptuo-motor deficits in children with congenital muscular dystrophy?
Diffuse white matter changes on MRI in children with congenital muscular dystrophy are consistently associated with perceptuo-motor difficulties and minor neurological soft signs.
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May identify CMD children at higher motor impairment risk; leaves open prospective validation before clinical adoption.
Mercuri et al. (1995) studied this question.
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