CRION: Need for a consensus for long term management

CRION is a newly recognized medical condition.It has emerged as a challenge for neurophysicians all over the world.It manifests as recurrent optic neuritis without evidence of any other neurological deficit or autoimmune disease.It is characterized by frequent relapses and remissions and steroids are the mainstay of treatment.Immunosuppressants also play a role in maintaining remission.We present a case with multiple episodes which have been refractory to multiple therapies.The case report dicusses the role of plasma exchange and Rituximab in the management of this challenging condition.