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Article1 October 1956LIPOGRANULOMATOUS PSEUDOSARCOIDNANCY E. WARNER, M.D., NATHAN B. FRIEDMAN, M.D.NANCY E. WARNER, M.D.Search for more papers by this author, NATHAN B. FRIEDMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-4-662 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBoeck's sarcoid, or true sarcoidosis, has been defined as a disease of unknown etiology, characterized pathologically by the presence in any organ or tissue of epithelioid cell tubercles with absent or inconspicuous necrosis. Refractile and apparently calcified bodies are frequently present in the giant cells of the tubercles, but acid-fast organisms are absent. The characteristic microscopic granulomas persist, although the lesions become scarred and hyalinized.Many investigators have observed that there are a variety of agents which evoke a pattern of tissue reaction similar to the lesions seen in Boeck's sarcoid.1-4Among these agents are acid-fast bacilli, includingMycobacterium tuberculosis...Bibliography1. Freiman DG: Sarcoidosis, New England J. Med. 239: 664, 1948. CrossrefMedlineGoogle Scholar2. Jaques WE: Sarcoidosis: a review and a proposed etiologic concept, Arch. Path. 53: 558, 1952. Google Scholar3. Engle RL: Sarcoid and sarcoid-like granulomas: a study of twenty-seven post-mortem examinations, Am. J. Path. 29: 53, 1953. MedlineGoogle Scholar4. Refvem O: The pathogenesis of Boeck's disease (sarcoidosis), Acta med. Scandinav. 149: Suppl. 294, 1954. Google Scholar5. PinkertonIverson HL: Histoplasmosis: three fatal cases with disseminated lesions, Arch. Int. Med. 90: 456, 1952. CrossrefGoogle Scholar6. 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FriedmanGarske NBGL: Inflammatory reactions involving sperm and the seminiferous tubules: extravasation, spermatic granulomas and granulomatous orchitis, J. Urol. 62: 363, 1949. CrossrefMedlineGoogle Scholar20. Berg JW: An acid-fast lipid from spermatozoa, Arch. Path. 57: 115, 1954. Google Scholar21. Mallory TB: Pathology of pulmonary fibrosis, including chronic pulmonary sarcoidosis, Radiology 51: 468, 1948. CrossrefMedlineGoogle Scholar22. WarrenRoot SHF: Lipoid-containing cells in the spleen in diabetes with lipemia, Am. J. Path. 2: 69, 1926. MedlineGoogle Scholar23. Refvem O: I. Chronic granulomas in the alimentary tract caused by minute mineral particles. II. "Boeck's disease" and occurrence of minute mineral particles. Preliminary report, Acta path. et microbiol. Scandinav. 25: 107, 1948. CrossrefMedlineGoogle Scholar24. Kent SP: Fat embolism in diabetic patients without physical trauma, Am. J. Path. 31: 399, 1955. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California*Received for publication March 2, 1956.From the Division of Laboratories, Cedars of Lebanon Hospital, and the Department of Pathology, University of Southern California.Presented before the Section on Pathology and Bacteriology at the 83rd Annual Session of the California Medical Association, Los Angeles, May 9-13, 1954.Requests for reprints should be addressed to Nancy E. Warner, M.D., Cedars of Lebanon Hospital, 4833 Fountain Avenue, Los Angeles 29, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOleocysts presenting as rectal tumoursFollicular (Mineral oil) lipidosis: I. Epidemiologic studies of involvement of the spleenMineral oil (follicular) lipidosisIdiopathic lipogranulomatosis of spleen and periaortic lymph nodes with noncaseating granulomas of liverPseudosarcoid granulomas in Hodgkin's diseaseClinicopathologic studies of 117 untreated patients subjected to laparotomy for the staging of Hodgkin's diseaseIsolated Granulomas in Hodgkin's DiseaseThe occurrence and significance of lipophage clusters in lymph nodes and spleenDie histologischen Ver�nderungen menschlicher Lymphknoten nach LymphographienStudy of 13 Cases of Association of Malignant Tumor and Regional Sarcoid Lymphoadenopathy�ber das Vorkommen cysten�hnlicher Hohlraumbildungen mit riesenzelliger Reaktion in den region�ren Lymphknoten bei Mamma- und CervixcarcinomenDie Fremdk�rperreaktion auf Gas und auf Fett in LymphknotenDiagnosis of Whipple's disease by peripheral lymph node biopsyDiagnostic significance of the muscle biopsySperm Granulomas Involving the Testis: Report of Two CasesMUSCLE INVOLVEMENT IN BOECK'S SARCOID*STANLEY L. WALLACE, RAFFAELE LATTES, JOHN PETER MALIA, CHARLES RAGAN, F.A.C.P.Experimental Evidence for an Allergic Basis for Granuloma Formation in Man 1 October 1956Volume 45, Issue 4Page: 662-673KeywordsBacteriologyEtiologyGiant cellsGranulomasLesionsMycobacterium tuberculosisNecrosisPhagocytosisSarcoidosis ePublished: 1 December 2008 Issue Published: 1 October 1956 PDF downloadLoading ...
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