What does this research mean for the field?

The spatial organization of oxygen donor atoms within carbohydrates dictates selective borate recognition, allowing boron to facilitate reversible higher-order organization across biological and engineered systems. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Synthesize the structural, thermodynamic, and stereochemical principles governing selective and reversible carbohydrate–borate interactions across natural and synthetic interfaces.

August 23, 2026OxygenOpen Access

Highly Oxygenated Biomolecules: Carbohydrates, Boron Complexes, and Their Biological Interfaces

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Authors

VDValery M. Dembitsky ATAlexander O. Terent’ev

Discussion

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Overview

Narrative review outlines carbohydrate–borate coordination principles across biological interfaces, highlighting mechanisms of selective recognition and applications in responsive biomaterials.

Key Points

Synthesize the structural, thermodynamic, and stereochemical principles governing selective and reversible carbohydrate–borate interactions across natural and synthetic interfaces.
Evaluated coordination chemistry across diverse carbohydrate classes, including pentoses, hexoses, oligosaccharides, polysaccharides, glycolipids, and membrane glycoconjugates.
Synthesized experimental and computational evidence from nuclear magnetic resonance spectroscopy, crystallography, mass spectrometry, calorimetry, and molecular dynamics simulations.
Spatial organization of oxygen-donor diol motifs, pH, hydration, and conformation govern reversible borate recognition and complex stability across carbohydrate classes.
Borate crosslinking provides essential structural stability in plant cell walls and microbial networks, with emerging evidence for roles in membrane-associated glycoconjugates.
Dynamic carbohydrate–borate coordination provides the mechanistic basis for engineering stimuli-responsive hydrogels, biosensors, supramolecular assemblies, and targeted drug-delivery platforms.

Cite This Study

Dembitsky et al. (2026) studied this question.

synapsesocial.com/papers/6a8aada77677a34114445e5f https://doi.org/10.3390/oxygen6030025

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August 23, 2026OxygenOpen Access

Highly Oxygenated Biomolecules: Carbohydrates, Boron Complexes, and Their Biological Interfaces

View Full Paper

Ask AI

Bookmark

Authors

VDValery M. Dembitsky ATAlexander O. Terent’ev

Discussion

Member takes

Overview

Narrative review outlines carbohydrate–borate coordination principles across biological interfaces, highlighting mechanisms of selective recognition and applications in responsive biomaterials.

Key Points

Synthesize the structural, thermodynamic, and stereochemical principles governing selective and reversible carbohydrate–borate interactions across natural and synthetic interfaces.
Evaluated coordination chemistry across diverse carbohydrate classes, including pentoses, hexoses, oligosaccharides, polysaccharides, glycolipids, and membrane glycoconjugates.
Synthesized experimental and computational evidence from nuclear magnetic resonance spectroscopy, crystallography, mass spectrometry, calorimetry, and molecular dynamics simulations.
Spatial organization of oxygen-donor diol motifs, pH, hydration, and conformation govern reversible borate recognition and complex stability across carbohydrate classes.
Borate crosslinking provides essential structural stability in plant cell walls and microbial networks, with emerging evidence for roles in membrane-associated glycoconjugates.
Dynamic carbohydrate–borate coordination provides the mechanistic basis for engineering stimuli-responsive hydrogels, biosensors, supramolecular assemblies, and targeted drug-delivery platforms.

Cite This Study

Dembitsky et al. (2026) studied this question.

synapsesocial.com/papers/6a8aada77677a34114445e5f https://doi.org/10.3390/oxygen6030025

View Full Paper

Ask AI

Bookmark