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August 23, 2026European Heart Journal - Digital HealthOpen Access

Health Electronic Assessment of Risks and Trends using Biometric Equipment and Technology (HEARTBEAT): Study Design and Rationale

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Authors

NMNassir F. MarroucheCMChristian MassadHFHan Feng

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Overview

Prospective single-arm study outlines smartwatch biometric and AI integration in 897 participants, aiming to enhance continuous cardiovascular risk prediction.

Key Points

  • To outline the design of a prospective study evaluating whether consumer smartwatch biometrics and artificial intelligence can identify cardiometabolic conditions and predict incident cardiovascular events.
  • Prospective, single-arm wearable study enrolling 897 participants in person or remotely starting October 10, 2024.
  • Data are captured via continuous smartwatch monitoring, a companion mobile application, and electronic medical record (EMR) extractions.
  • Participants are followed for 12 months with ongoing outcome adjudication using EMR reviews and app-based surveys.
  • Establishes a framework to evaluate whether consumer-grade wearables can provide clinically validated signals for detecting occult cardiovascular disease.
  • Details analytical strategies using artificial intelligence to build biometric risk profiles for proactive cardiovascular risk mitigation.

Cite This Study

Marrouche et al. (2026) studied this question.

synapsesocial.com/papers/6a8aae407677a34114447258https://doi.org/10.1093/ehjdh/ztag132
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