Recently we have investigated the interaction of calcium( 11) ions with double-helical calf thymus DNA ( C T DNA) in dilute isotropic solutions, using 43Ca-nmr.'*2 We studied sonicated high molecular weight C T DNA with and without the presence of terminal phosphate groups at ends and nicks, and nucleosome core-length DNA from calf thymus. At low calcium to DNA phosphate ratios (Ca/ DNA < O.l), we found that the association of Ca'+ with
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Braunlin et al. (1991) studied this question.
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