Pseudohypoparathyroidism

Case Reports1 February 1962PseudohypoparathyroidismCase Report with Observations on the Difficulty in Confirming the DiagnosisMARTIN I. SURKS, M.D., DAVID LEVENSON, M.D.MARTIN I. SURKS, M.D.Search for more papers by this author, DAVID LEVENSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-2-282 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1942, Albright and colleagues (1) introduced the term pseudohypoparathyroidism (PHP) to describe three previously diagnosed cases of idiopathic hypoparathyroidism (IHP) that showed similar abnormalities of serum calcium and phosphate but exhibited refractoriness to parathyroid hormone. The distinguishing clinical findings in this syndrome included short stature, round face, abnormal shortening of the metacarpal and metatarsal bones, and subcutaneous calcifications.Since 1942, fifty-nine cases of pseudohypoparathyroidism have been reported in the world literature (2-15). It is the purpose of this report to present an unusual example of this disorder and to discuss the difficulties in confirming the diagnosis when the clinical...References1. ALBRIGHTBURNETTSMITHPARSON FCHPHW: Pseudohypoparathyroidism, an example of the Seabright-Bantam syndrome. Report of three cases. Endocrinology 30: 922, 1942. Google Scholar2. BRONSKYKUSHNERDUBINSNAPPER DDSAI: Idiopathic hypoparathyroidism and pseudohypoparathyroidism: case reports and review of the literature. Medicine 37: 317, 1958. CrossrefMedlineGoogle Scholar3. TAYLORBUFFMIRE ABDK: Pseudohypoparathyroidism—report of a case. Ann. Intern. Med. 47: 356, 1957. LinkGoogle Scholar4. MACKAY NR: Pseudohypoparathyroidism. New Zeal. 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LIEBER, M.D.The ParathyroidsMedical genetics 1962References 1 February 1962Volume 56, Issue 2Page: 282-288KeywordsBoneCalciumExcretionHormonesHypoparathyroidismParathyroidParathyroid hormonePhosphatesPseudohypoparathyroidismThyroid Issue Published: 1 February 1962 PDF DownloadLoading ...