With the aid of selected examples an overview is given of the development trends in highly discriminative reactions using organoaluminum compounds. (1) Isomerization of substituted oxiranes into allyl alcohols has been effected both stereo‐ and regioselectively by means of a new organoaluminum reagent, diethylaluminum 2,2,6,6‐tetramethylpiperidide (DATMP); this reaction which provides a new route for the regiospecific transformation of allyl alcohols into 1,3‐dienes. (2) A novel nonenzymic heterolysis of allylic phosphates of terpenoids has been effected by organoaluminum compounds and has enabled development of a new method for the selective synthesis of cyclic terpenes. (3) The reductive condensation of α‐haloketones with carbonyl compounds in the presence of diethylaluminum chloride and zinc affords β‐hydroxy‐carbonyl derivatives in good yields with exclusion of undesired self‐condensations products.
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Yamamoto et al. (1978) studied this question.