Clinical Reasoning: A 42-year-old man with severe headache, fever, and acute coma

A 42-year-old man underwent brain MRI at a local health facility for severe headache and was found to have a pituitary adenoma. Two days later, he presented to the emergency department of our hospital with high fever and sudden-onset coma. The patient had a history of intermittent moderate headache in the recent 8 months. No medical history of vascular risk factors was identified.