Central Regulation of Sympathetic Ganglia Development: Heterogeneous Response of Paravertebral, Prevertebral, and Terminal Gangliaa

These studies expand previous observations regarding the central control of neuronal maturation and indicate that paravertebral, prevertebral, and terminal ganglia are all under central influences, but in varying degrees. These variations are probably related to the relative contributions that central pathways exert on specific peripheral neuronal populations during growth and development as well as the various roles of more peripheral developmental modulators such as target organs and hormones, especially in the case of the HG. It is apparent, therefore, that during development central injury may result in heterogeneous deficits depending on the unique intrinsic and extrinsic environment that each ganglion population shares.