Key result
Percutaneous transcatheter device closure was technically successful in a patient with serpiginous post-MI ventricular septal rupture, but the patient died on day 3 from sepsis and multiorgan failure.
Why the study?
Postmyocardial infarction ventricular septal rupture carries high mortality, and transcatheter device closure is particularly challenging in serpiginous defects.
Case Report (n=1)
Highlights the technical feasibility but high mortality risk of percutaneous transcatheter device closure for serpiginous post-MI VSR in patients with cardiogenic shock.
Answers are grounded in this paper and cite their sources.
Supports percutaneous closure feasibility in complex post-MI VSR; leaves open survival benefit versus surgery.
Ventricular septal rupture (VSR) after acute myocardial infarction is rare and associated with high mortality despite surgical repair. Percutaneous transcatheter device closure has emerged as an alternative to surgical repair in high-risk patients or as a bridge to delayed surgical repair. Not only the timing but also the morphology of defect matters, and in patients with serpiginous ventricular septal defect, device deployment is challenging. We report a patient with cardiogenic shock due to serpiginous VSR following myocardial infarction who underwent percutaneous transcatheter device closure successfully but expired on the 3 rd day following the procedure due to sepsis and multiorgan failure.
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Khanra et al. (2020) conducted a case report in Ventricular septal rupture after acute myocardial infarction (n=1). Percutaneous transcatheter device closure was evaluated on Clinical outcome. Percutaneous transcatheter device closure was technically successful in a patient with serpiginous post-MI ventricular septal rupture, but the patient died on day 3 from sepsis and multiorgan failure.
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