Drug Extravasation as a Complication of Venous Access Ports

Brief Reports1 June 1985Drug Extravasation as a Complication of Venous Access PortsWILLIAM P. REED, M.D., KATHRYN A. NEWMAN, R.N., MARK M. APPLEFELD, M.D., FREDERICK J. SUTTON, M.D.WILLIAM P. REED, M.D.Search for more papers by this author, KATHRYN A. NEWMAN, R.N.Search for more papers by this author, MARK M. APPLEFELD, M.D.Search for more papers by this author, FREDERICK J. SUTTON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-6-788 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough Hickman catheters provide safe and reliable venous access for chemotherapy over many months (1, 2), infectious complications (3, 4) and the need for sophisticated and attentive care to maintain patency of the catheter for the duration of therapy (5) have encouraged the development of alternative devices. Access ports have recently been introduced (6, 7) to avoid these problems of maintenance and sepsis. The ports are implanted subcutaneously and have a small reservoir attached to the external end of the venous access tubing. Entry to the device for drug administration is gained by directing a specially designed needle through the...References1. PRESSRAMSEYLARSONFEFERHICKMAN OPEAR. Hickman catheter infections in patients with malignancies. Medicine (Baltimore). 1984;63:189-200. CrossrefMedlineGoogle Scholar2. REEDNEWMANDE JONGHSCHIMPFFWIERNIK WKCSP. Seventy-five patient years experience with right atrial catheters for chemotherapy. In: KOOTSTRA G, JORNING PJG, eds. Access Surgery. Lancaster, England: MTP Press; 1983:275-80. CrossrefGoogle Scholar3. WADESCHIMPFFNEWMANWIERNIK JSKP. Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia. Ann Intern Med. 1982;97:503-8. LinkGoogle Scholar4. BEGALAMAHERCHERRY JHJ. Risk of infection associated with the use of Broviac and Hickman catheters. Am J Infect Control. 1982;10:17-23. CrossrefMedlineGoogle Scholar5. REEDNEWMANDE JONGH WKC. Prolonged venous access for chemotherapy by means of the Hickman catheter. Cancer. 1983;52:185-92. CrossrefMedlineGoogle Scholar6. NIEDERHUBERENSMINGERGYVESLIEPMANDOANCOZZI JWJMKE. Totally implanted venous and arterial access system to replace external catheters in cancer treatment. Surgery. 1982;92:706-12. MedlineGoogle Scholar7. SCHUMANBRADYGALENWINTERS EAWV. Implanted venous access ports have significantly fewer complications than Hickman catheters [Abstract C-368]. Proc Am Soc Clin Oncol. 1984;3:95. Google Scholar8. APPLEFELDNEWMANGROVE MKW. Intermittent, continuous outpatient dobutamine infusion in management of congestive heart failure. Am J Cardiol. 1983;51:455-8. CrossrefMedlineGoogle Scholar9. HEIMBACHIVEY DT. Technique for placement of a permanent home hyperalimentation catheter. Surg Gynecol Obstet. 1976;143:635-6. Google Scholar10. IGNOFFOFRIEDMAN RM. Therapy of local toxicities caused by extravasation of cancer chemotherapy drugs. Cancer Treat Rep. 1980;7:17-27. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Maryland School of Medicine Baltimore, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRecommendations for Management of Noncytotoxic Vesicant ExtravasationsVasopressor and Inotrope Use in Canadian Emergency Departments: Evidence Based Consensus GuidelinesVasopressors and Inotropes5-Fluorouracil5-Fluorouracil5-Fluorouracil (z.B. 5-Fluorouracil „Ebewe“)Vascular Access for CancerIatrogenic Cardiovascular Complications: Part II. 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LOKICH, M.D., CHERIE MOORE, R.N.Venous Access PortsIAN G. KERR, M.D., F. R. C. P. (C), NEILL ISCOE, M.D., F. R. C. P. (C), MARICA SONE, R. N., S. HANNA, M.D., F. R. C. S.(C)Drug Extravasation and the Port-a-Cath SystemSTEPHEN B. STRUM, M.D., JONATHAN E. MCDERMED, Pharm.D.5-Fluorouracil (z.B. 5-Fluorouracil „Ebewe“, Ribofluor®) 1 June 1985Volume 102, Issue 6Page: 788-790KeywordsCathetersChemotherapyDrug administrationDrug therapySepsis Issue Published: 1 June 1985 PDF DownloadLoading ...