Key result
The ReCaP study protocol describes a longitudinal observational study of 100 endurance runners to assess cardio- and neurophysiological adaptations to marathon running.
Why the study?
Regular physical activity reduces mortality from cardiovascular and neuropsychiatric diseases, but acute and prolonged cardio- and neurophysiological responses to marathon running need further investigation.
Does marathon running induce acute and prolonged cardio- and neurophysiological adaptations in endurance runners?
Observational (n=100)
Does marathon running induce acute and prolonged cardio- and neurophysiological adaptations in endurance runners?
This study protocol outlines a multimodal longitudinal assessment of the cardio- and neurophysiological adaptations to marathon running.
Answers are grounded in this paper and cite their sources.
Protocol for marathon adaptations in runners warrants clinical caution; leaves open causal effects until results emerge.
Regular moderate physical activity (PA) has been linked to beneficial adaptations in various somatic diseases (e.g. cancer, endocrinological disorders) and a reduction in all-cause mortality from several cardiovascular and neuropsychiatric diseases. This study was designed to investigate acute and prolonged exercise-induced cardio- and neurophysiological responses in endurance runners competing in the Munich Marathon. ReCaP (Running effects on Cognition and Plasticity) is a multimodal and longitudinal experimental study. This study included 100 participants (20-60 years). Six laboratory visits were included during the 3-month period before and the 3-month period after the Munich marathon. The multimodal assessment included laboratory measurements, cardiac and cranial imaging (MRI scans, ultrasound/echocardiography) and neurophysiological methods (EEG and TMS/tDCS), and vessel-analysis (e.g. retinal vessels and wave-reflection analyses) and neurocognitive measurements. The ReCaP study was designed to examine novel exercise-induced cardio- and neurophysiological responses to marathon running at the behavioral, functional and morphological levels. This study will expand our understanding of exercise-induced adaptations and will lead to more individually tailored therapeutic options.
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Roeh et al. (2019) conducted an observational in Healthy endurance runners (n=100). Marathon running was evaluated on Acute and prolonged exercise-induced cardio- and neurophysiological responses. The ReCaP study protocol describes a longitudinal observational study of 100 endurance runners to assess cardio- and neurophysiological adaptations to marathon running.
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