We present 3 cases of Neisseria meningitidis with varied clinical presentations, including meningococcemia, meningitis, and pneumonia. Our cases suggest an association between concomitant bacterial and viral infections, including group A streptococcus and adenovirus, and an increased risk of invasive Neisseria infections. PCR data are a useful adjunct to bacterial cultures for the diagnosis. Our case series exemplify the continued high mortality of N. meningitides and highlights the need for more immunogenic vaccines for prevention.
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Crum et al. (2005) studied this question.
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