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Abstract An efficient and convenient three‐component A3 coupling reaction of aldehyde, amine and alkyne via CH activation with CuI alone as the catalyst in PEG is developed, providing a wide range of propargylamines with yields ranging from moderate to excellent. Additionally, the catalyst system was recovered and reused several times without evident loss in activity. Copyright © 2010 John Wiley & Sons, Ltd.
Zhang et al. (2010) studied this question.