This book, first published in 1987, is now in its third edition which at:ests both to its popularity and the recent rapid progress in clinical vi ology.It provides an overview of the subject which is suitable for a ge:leral medical audience, including medical students, as well as for cliaical virologists.However, it is not exhaustive in detail nor is it cc-npletely referenced.the editors have enlisted 44 authors for 25 chapters, each of which deals with either a group of viruses (e.g.hepatitis viruses) or a single agent (e.g.cytomegalovirus).Each topic is covered from the point of vi,,w of basic virology, pathogenesis, epidemiology, clinical features, diagnosis, treatment and prevention.All the chapters have been revised al~d some completely rewritten in the light of new information, and many of the authors stress the development and application of m,)lecular biological techniques to diagnosis.The chapters on rubella, h~man parvovirus B19, viruses associated with acute diarrhoeal disease al~d filoviruses are particularly up to date, but the chapter on re.roviruses is rather limited given the enormous clinical problems p, sed, in particular, by HIV.As regards the hepatitis viruses, the clinical significance of the different genotypes of hepatitis C virus
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Kristian Helin (1996) studied this question.