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April 1, 1990Antimicrobial Agents and Chemotherapy

Antifungal activity in human cerebrospinal fluid and plasma after intravenous administration of Allium sativum

L. E. Davis Jinkun Shen Yongyang Cai

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Abstract

Commercial Allium sativum (garlic) extract was given intravenously to two patients with cryptococcal meningitis and three patients with other types of meningitis. Plasma titers of anti-Cryptococcus neoformans activity rose twofold over preinfusion titers. Anti-C. neoformans activity was detected in four of five cerebrospinal fluid samples but not in pooled normal cerebrospinal fluid.

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Davis et al. (1990) studied this question.

synapsesocial.com/papers/6a8af6bd52e1a91077e95357 https://doi.org/10.1128/aac.34.4.651

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