In article number 1707365, Patrick Couvreur, Christian Serre, and co-workers evaluate the biomedical applications of metal–organic frameworks at the preclinical stage, for pharmacological applications or toxicity evaluation. Current surface-engineering approaches, in vivo studies, and their prospects are considered. The back cover image illustrates the circulation of drug-loaded MOF nanoparticles in a blood vessel. In particular, nanosized cages of MIL-100(Fe) loaded with Ibuprofen drug are represented. Cover project designed by Maria Mikołajczak-Zygmańska.
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Simón‐Yarza et al. (2018) studied this question.
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