Effetto Delltdrossilamina e della sodio Azide Sull'Accrescimento di Alcuni Tumori Trapiantabili

The action of hydroxilamine and sodium azide has been studied on Walker adenocarcinoma of rats and Ehrlich adenocarcinoma and sarcoma 180 of mice. The tumour bearing animals were subcut injected with daily doses of 60 mg/kg for the first substance and 14 mg/kg for the second one. Hydroxilamine does not modify the growth of Walker adenocarcinoma and sarcoma 180; while a diminution of 50 per cent about is observed for Ehrlich adenocarcinoma. The growth of the three tumours under examination is reduced by sodium azide. At the end of the experiment, the weights of Walker and Ehrlich adenocarcinoma and sarcoma 180 are respectively the 37, 50 and 50 per cent in comparison to those of the control tumours.