Case Reports1 July 1958SYSTEMIC CANDIDIASIS (MONILIASIS) COMPLICATING TREATMENT OF BACTERIAL ENDOCARDITIS, WITH REVIEW OF LITERATURE AND REPORT OF APPARENT CURE OF ONE CASE WITH PARENTERAL MYCOSTATINE. RICHARD HARRELL, M.D., GEORGE R. THOMPSON, M.D.E. RICHARD HARRELL, M.D.Search for more papers by this author, GEORGE R. THOMPSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-1-207 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWith the advent of antibiotics, acute bacterial endocarditis, which once was nearly always fatal, has been successfully treated. However, with antibiotic therapy there is an increasing number of cases of candidiasis. We wish to report two cases (one ending fatally) with systemic candidiasis complicating the usual antibiotic treatment of bacterial endocarditis. The second case was apparently cured and is alive and well.Candida infections are commonly seen occurring in the mouth, oropharynx, vagina, rectum, gastrointestinal tract and the skin. A number of cases of bronchopulmonary candidiasis have also been reported.1, 2In addition, several cases of Candida meningitis are recorded....Bibliography1. HiattMartin JSDS: Recovery from pulmonary moniliasis following serum therapy, J. A. M. A. 130: 205-206 (Jan. 26) 1946. MedlineGoogle Scholar2. KlaphekeHarter MAJS: Report of a case of systemic moniliasis, Dis. of Chest 24: 332-335 (Sept.) 1953. CrossrefMedlineGoogle Scholar3. GeigerWennerAxilrodDurlacher AJHAHDSA: Mycotic endocarditis and meningitis, Yale J. Biol. and Med. 18: 259-268 (Mar.) 1946. MedlineGoogle Scholar4. FriedmanDonaldson NDL: Systemic mycosis with mycotic endocarditis, Arch. Path. 27: 394-395 (Feb.) 1939. Google Scholar5. JoachimPolayes HSH: Subacute endocarditis and systemic mycosis (Monilia), J. A. M. A. 115: 205-208 (July 20) 1940. CrossrefGoogle Scholar6. WiklerWilliamsDouglassEmmonsDunn AEGEDCWRC: Mycotic endocarditis, J. A. M. A. 119: 333-337 (May 23) 1942. CrossrefGoogle Scholar7. Pasternack JG: Subacute monilial endocarditis, Am. J. Clin. Path. 12: 496-505 (Sept.) 1942. CrossrefGoogle Scholar8. Zimmerman LE: Candida and Aspergillus endocarditis, Arch. Path. 50: 591-605 (Nov.) 1950. MedlineGoogle Scholar9. Caplan H: Monilial (Candida) endocarditis following treatment with antibiotics, Lancet 2: 957-958 (Nov. 5) 1955. CrossrefGoogle Scholar10. Rankin NE: Disseminated aspergillosis and moniliasis associated with agranulocytosis and antibiotic therapy, Brit. M. J. 1: 918-919 (Apr. 25) 1953. CrossrefMedlineGoogle Scholar11. BrownProppGuestBeebeEarly CSMRTL: Fatal fungus infections complicating antibiotic therapy, J. A. M. A. 152: 206-207 (May 16) 1953. CrossrefMedlineGoogle Scholar12. WolfeHenderson EIFW: Mycotic endocarditis, report of a case, J. A. M. A. 147: 1344-1347 (Dec. 1) 1951. CrossrefMedlineGoogle Scholar13. KunstadterMacLeanGreengard RHHJ: Mycotic endocarditis due to Candida albicans , J. A. M. A. 149: 829-832 (June 28) 1952. CrossrefMedlineGoogle Scholar14. Robertson JA: Systemic moniliasis, California Med. 84: 115-117 (Feb.) 1956. MedlineGoogle Scholar15. ZimmermanFrutcheyGibbes SLLJH: Meningitis due to Candida albicans, with recovery, J. A. M. A. 135: 145-147 (Sept. 20) 1947. CrossrefMedlineGoogle Scholar16. SchabergHildesWilt AJAJC: Disseminated candidiasis, Arch. Int. Med. 95: 112-117 (Jan.) 1955. CrossrefGoogle Scholar17. Robinson HM: Moniliasis complicating antibiotic therapy, Arch. Dermat. and Syph. 70: 640-652 (Nov.) 1954. CrossrefGoogle Scholar18. Kligman AM: Are fungus infections increasing as a result of antibiotic therapy? J. A. M. A. 194: 979-983 (July 12) 1952. CrossrefGoogle Scholar19. HuppertMacPhersonCazin MDAJ: Pathogenesis of Candida albicans infections following antibiotic therapy, J. Bact. 64: 171-176 (Feb.) 1953. CrossrefGoogle Scholar20. Reiches AJ: Antibiotic sensitivity and moniliasis, Arch. Dermat. and Syph. 64: 604-606 (Nov.) 1951. CrossrefGoogle Scholar21. PappenfortSchnall RBES: Moniliasis in patients treated with Aureomycin, Arch. Int. Med. 88: 729-735 (Dec.) 1951. CrossrefGoogle Scholar22. BratlundHolten HC: Moniliasis of mucous membranes and lungs as a complication of treatment with antibiotics, corticotropin and cortisone, Danish M. Bull. 1: 79-84 (June) 1954. MedlineGoogle Scholar23. MankowskiLittleton ZTBJ: Action of cortisone and ACTH on experimental fungus infections, Antibiotics and Chemotherapy 4: 253-258 (Mar.) 1954. Google Scholar24. Seligmann E: Virulence enhancement of C. albicans by antibiotics and cortisone, Proc. Soc. Exper. Biol. and Med. 83: 778-781 (Aug.-Sept.) 1953. CrossrefMedlineGoogle Scholar25. Niel K: Zur Klinik der Candidainfektionen, Klin. Med., Wien 8: 49-54 (Feb.) 1953. Google Scholar26. Kohlmeier W: Zur Kenntnis der Candidainfektionen, Klin. Med., Wien 8: 54-61 (Feb.) 1953. Google Scholar27. Luttgens WF: Endocarditis in "main line" opium addicts, A. M. A. Arch. Int. Med. 83: 653-664 (June) 1949. CrossrefGoogle Scholar28. WesslerBrowne SHR: Candida albicans infection with blood stream invasion; Report of a case, Ann. Int. Med. 22: 886-890 (June) 1945. LinkGoogle Scholar29. Parrillo OJ: Disseminated mycotic disease, report of three cases, J. A. M. A. 144: 747-749 (Oct. 28) 1950. CrossrefMedlineGoogle Scholar30. Generalized moniliasis—case report, Arch. Dermat. and Syph. 68: 105-106 (July) 1953. Google Scholar31. GausewitzJonesWorley PLFSG: Fatal generalized moniliasis, Am. J. Clin. Path. 21: 41-49 (June) 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Received for publication November 21, 1956.From the Departments of Dermatology and Syphilology and Internal Medicine, University of Michigan Medical School, and the University Hospital, Ann Arbor, Michigan.Requests for reprints should be addressed to E. Richard Harrell, M. D., Department of Dermatology, University Hospital, Ann Arbor, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCandida endocarditis complicating treatment of native valve bacterial endocarditisInfective endocarditis as a result of medical progressThe role of valve replacement in the treatment of fungal endocarditisCandida endocarditis with femoral emboliTreatment of infective endocarditis—1973Fungal endocarditis following cardiovascular surgeryThe role of antibiotics in the pathogenesis of Candida infectionsSYSTEMIC CANDIDIASISABDOMINAL AORTIC ANEURYSMSAcute monilial infection as a cause of deathSurgical Cure of Candida albicans Endocarditis with Open-Heart SurgeryThe Significance of Candida albicans in Human Sputum 1 July 1958Volume 49, Issue 1Page: 207-215KeywordsAntibioticsCandidaCandidiasisEndocarditisHospital medicineRectumSepsisSkin infectionsStaphylococcus aureusVagina ePublished: 1 December 2008 Issue Published: 1 July 1958 PDF downloadLoading ...
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