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October 4, 2013The Open Critical Care Medicine JournalOpen Access

Therapeutic Mild Hypothermia and the Pharmacokinetics of Drugs in Trauma Brain Injury (TBI) Patients with a Focus on Sedation, Anticonvulsant and Antibiotic Therapy

F. Carlotta Bagna

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Abstract

Background: Therapeutic hypothermia may alter both the pharmacokinetic (PK) and dynamics (PD) of the commonly used drugs in critical care. To achieve maximum benefit, medication dosage and schedules should be optimized.

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F. Carlotta Bagna (2013) studied this question.

synapsesocial.com/papers/6a8b22fa90fae8fd47e969d9 https://doi.org/10.2174/1874828701306010031

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