Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

Matthew E. Larsen; Olivia R. Buonarati; Hai Qian; Johannes Hell; K. Ulrich Bayer

doi:10.1016/j.jbc.2023.104706

April 13, 2023Journal of Biological ChemistryOpen Access

Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

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Abstract

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-channels and specifically required β2-ARs. Taken together, these results indicate that Iso transforms LTD stimuli to LTP signals by switching CaMKII movement and GluN2B binding to LTP mode.

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Larsen et al. (2023) studied this question.

synapsesocial.com/papers/6a8b296e5ef9ff12d7893a95 https://doi.org/10.1016/j.jbc.2023.104706

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Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

Abstract

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Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

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