In 4 patients with diabetes mellitus and azotemia, acute renal failure developed after intravenous urography. All had been dehydrated before examination. This, combined with severe vascular disease and proteinuria, appears to cause failure associated with intravenous urography. In all patients with azotemia, and particularly in those with multiple myeloma or diabetes mellitus, adequate hydration before intravenous urography is obligatory. Afterward, fluid intake should be continued, with urine volume being recorded hourly to indicate need for mannitol treatment if the volume decreases progressively.
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Pillay et al. (1970) studied this question.
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