Key result
Candesartan is an effective angiotensin II receptor blocker for treating hypertension, offering cerebro- and cardioprotective effects and benefits in diabetic nephropathy.
Why the study?
Does candesartan effectively treat hypertension and provide organ protection compared to other angiotensin receptor blockers?
Does candesartan effectively treat hypertension and provide organ protection compared to other angiotensin receptor blockers?
Candesartan is an effective angiotensin receptor blocker for hypertension with favorable pharmacokinetic properties and additional cerebro-cardioprotective and nephroprotective benefits.
Answers are grounded in this paper and cite their sources.
May support candesartan selection in hypertension with organ protection; leaves open head-to-head comparisons versus other ARBs.
Candesartan is a selective angiotensin II receptor blocker type 1. The distinctive features of its pharmacokinetics and pharmacodynamics are long duration of antihypertensive action, high selectivity and good bioavailability. In the treatment of hypertension, candesartan can effectively prevent morning rise in blood pressure. For preparation peculiar cerebro-and cardioprotective effects, the ability to reduce the risk of new cases of diabetes. The drug is effective in the treatment of nephropathy different genesis, including in patients with a marked reduction in renal function. Metabolic neutrality, the ability to prevent the development of micro-and macroangiopathy can recommend this angiotensin receptor blocker in the treatment of diabetic patients. Favorable profile of the pharmacokinetic properties of an advantage in efficacy of candesartan in comparison with other drugs of the same group.
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Л. О. Минушкина (2014) conducted a review in Hypertension. Candesartan vs. Other angiotensin receptor blockers was evaluated. Candesartan is an effective angiotensin II receptor blocker for treating hypertension, offering cerebro- and cardioprotective effects and benefits in diabetic nephropathy.
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