A novel route to imidazoles and their use for the synthesis of purines and 4,6‐dihydro‐1,2‐dimethyl‐8‐phenylimidazo[4,5‐e]‐1,4‐diazepin‐5(1H)‐on. Recently it has been shown [2] that pyrimidines are available from Thorpe‐Ziegler cyclization of the appropriate dinitriles. As an extension of this work, a novel route to imidazoles has been developed. It has been demonstrated that these imidazole derivatives are valuable intermediates for the synthesis of purines by application of standard procedures. The use of these imidazoles has enabled the preparation of some derivatives not accessible by other methods.
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Albrecht Edenhofer (1975) studied this question.
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