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Non-specific esterase in the whole-body section of rat was demonstrated histochemically. A strong activity was seen in the liver, kidney cortex, pancreas, small intestine and Harderian gland and a weak activity in the hair follicles. The reaction was almost completely inhibited with 10-4M DFP except that in the hair follicles and Harderian gland, while not inhibited with 10-4M eserin. The usefulness of this method, “whole-body histochemistry”, was discussed.
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Fukuda et al. (1974) studied this question.
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