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February 1, 1994Cell Proliferation

Origin and evolution of binucleate cells in cultures of HEp‐2 cells

Antonio Serrano Vicente Rodilla Julio Pellicer‐Porres J. Pertusa

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Abstract

The origin and evolution of binucleate cells in cultures of HEp-2 cells have been studied by means of interval photography and time-lapse video-recording. Binucleate cells most frequently formed by the fusion of two sister cells born in a previous mitosis. The study of binucleate cells has shown that they are a cellular type able to successfully undergo mitosis. However, the mitosis may be bipolar, tripolar or multipolar. The daughter cells arising from these divisions do not follow a clear pattern in the number of nuclei they have, instead showing a wide range of possibilities.

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Cite This Study

Serrano et al. (1994) studied this question.

synapsesocial.com/papers/6a8b91559ac394ad33cab0da https://doi.org/10.1111/j.1365-2184.1994.tb01410.x

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