Paradoxical coronary embolism should be considered in patients with DVT who present with myocardial infarction and moderate enzyme elevation, as PFO is highly prevalent.
Answers are grounded in this paper and cite their sources.
May support considering paradoxical embolism in DVT-MI with moderate enzymes; leaves open validation of prevalence and screening utility.
Myocardial infarctions (MI) are relatively common in people with deep vein thrombosis (DVT). In fact, the rate of myocardial infarction has been reported to be greater in adults with DVT as compared to those without DVT and recent studies have shown interest in quantifying the relationship with MI and DVT. However, cryptogenic nature of MI in these individuals is underestimated. Approximately one-fourth of the US populations are estimated to have a patent foramen ovale (PFO). Of note, since MI being the single largest cause of mortality, a large number of these patients have a PFO. The high percentage of myocardial infarction in patients with a PFO has not been addressed in the literature appropriately before and might have been overlooked because most of the patients with infarctions had an uncomplicated course and only moderate enzyme elevation.
No takes yet. Share an insight, caveat, or question.
Shridhar et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: