Probable assignment of the locus determining human red cell acid phosphatase ACP1 to chromosome 2 using somatic cell hybrids

SUMMARY Twelve independent interspecific hybrid lines, from six different crosses, together with nine subclones, were tested for the presence of the human enzymes ACP1, MOR‐S and ICD‐S. The hybrids were also tested for a total of 27 other human enzymes. With one exception the data were consistent with the synteny of ACP1, MOR‐S and ICD‐S. Detailed chromosome analysis of the subclones confirmed the assignment of these loci to chromosome 2. In the remaining hybrid chromosome 2 was present, together with MOR‐S and ICD‐S but ACP1 was not seen. Possible explanations for this discrepancy are discussed.