{7 H-1,2,4-triazolo[1,5-d]tetrazol-6-ylsulfanyl} acetic acid hydrazide was utilized by different reagent, namely isothiocyanates, formic acid, triethyl orthoformate, and carbon disulfide, to yield the corresponding compounds, which were cyclized to construct 1,2,4-triazoles, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles. The structure of the products was deduced through physicochemical as well as spectral data (IR, 1 H NMR, and MS). Representative members of the prepared compounds were tested for antimicrobial activity.
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Taha et al. (2007) studied this question.
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