Edeine D is pentapeptide amide produced with other edeines by Bacillus brevis Vm4 strain. This antibiotic is composed of glycine (Gly), isoserine (Ise), 2,3‐diaminopropionic acid (A2pr), 2,6‐diamino‐7‐hydroxyazelaic acid (A2ha), 3‐amino‐3‐phenyl‐propionic acid (Iph), and spermidine (Spe). Partial and full acid hydrolysis, enzymatic degradation with carboxypeptidase B, periodate‐permanganate oxidation and examination of Dnp‐derivatives suggested the following structure of edeine D: (S)‐Iph‐(S)‐Ise‐(S)‐A2 pr‐(R,S,R)‐A2 ha‐(Gly‐Spe).
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Könitz et al. (1985) studied this question.
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