Children were examined for caries activity, and their salivary IgA was evaluated for reactivity to antigens of cariogenic bacteria by an enzyme-linked immunosorbent assay (ELISA). IgA levels to Streptococcus mutans were higher in children with no detectable caries. Analysis of IgA specific for Lactobacillus casei, teichoic acid, and glucan revealed no protective role for these specificities in children.
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Bolton et al. (1982) studied this question.
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