Nucleic Acid Phosphorus of Mouse Pancreas After Pilocarpine Administration

SUMMARY No statistically significant variations were observed in either ribonucleic . or desoxyribonucleic acid phosphorus levels in mouse pancreas 20 minutes and 1, 4, 7, and 12 hours after intravenous pilocarpine administration, compared with the controls. Xo variation in RNAP content could there- fore be related to the protein synthesis that follows pilocarpine adminis- tration. The bearing of these results on previous histochemical data is discussed. BIBLIOGRAPHY 1. Caspersson, T., in Nucleic acid, Symposia of the Society for Experimental Biol- ogy, Cambridge, 1, 127 (1947). 2. Brachet, J., Embryologie chimique, Paris, 259 (1947). 3. Davidson, J. N., The biochemistry of nucleic acids, London, chapter 9 (1950). 4. Eliasson, N. A., Hammarsten, E., Reichard, P., Aqvist, S., Thorell, B., and Ehrensvlird, G., Acta &em. &and., 6, 431 (1951). 5. Covell, W. P., Anat. Rec., 40, 213 (1928). 6. Babkin, B. P., The secretory mechanism of the digestive glands, New York, 71 (1950). 7. Caspersson, T., Landstroem-Hyden, H., and Aquilonius, L., Chromosoma, 2, 111 (1941). 8. de Robertis, E., Nufies, I., and de1 Conte, E., Rev. Sot. Argent. biol., 21, 214 (1945). 9. van Weel, P. B., and Engel, C., 2. vergl. Physiol., 26, 67 (1938). 10. van Weel, P. B., 2. vergl. Physiol., 2’7, 311 (1939). ’ 11. Hirsch, G. C., 2. Zellforsch., 16, 36 (1932). 12. Ries, E., 2. Zellforsch., 22, 523 (1935). 13. Noback, C. R., and Montagna, W., Am. J. And, 81,343 (1947). 14. Cappellin, M., and Gasparini, F., Mon. zool. ital., 69, suppl., 133 (1951). 15. Schmidt, G., and Thannhauser, S. J., J. Biol. Chem., 161, 83 (1945). 16. Davidson, J. N., Leslie, I., and Waymouth, C., Biochem. J., 44, 5 (1949). 17. Rabinovitch, M., Rothschild, H. A., and Junqueira, L. C. II., J. Biol. Chem., 194, 835 (1952). 18. Schneider, W. C., J. Biol. Chem., 164, 747 (1946). by guest, on July 13, 2011www.jbc.orgDownloaded from