Drug-associated adverse hepatic reactions could be severe, mostly idiosyncratic, that is; they rarely occur, even if administered in the therapeutic dose and are not detected during developmental phase; any substance could be hepatotoxic, however, some drugs could have a higher potential as non-steroidal anti-inflammatory drugs and among them, diclofenac.
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Bizueto-Rosas et al. (2021) studied this question.
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